PhD Positions in Molecular Cancer Research - Investigating Therapy Resistance (f/m/d)

Faculty of Medicine Tübingen, iFIT Cluster of Excellence, index number 7735

Part-time:

65 % Limited:

36 months 1 Start of work:

01.10.2026 Application deadline:

26.08.2026 TV-L

i.d.R. E13 2 Our research within the iFIT Cluster of Excellence is dedicated to one of the greatest challenges in oncology: Overcoming therapy resistance in tumors, with a particular focus on liver and gastrointestinal cancers. By uncovering the molecular mechanisms that enable tumors to evade treatment, we aim to develop innovative therapeutic strategies that ultimately improve patient outcomes.

Tasks

• Investigate the molecular mechanisms underlying therapy resistance in liver and gastrointestinal cancers using state-of-the-art technologies as part of an independent PhD research project (leading to the degree of Dr. rer. nat.)
• Perform and analyze innovative experiments to identify and evaluate novel therapeutic strategies with translational relevance
• Present your research findings at lab meetings and international conferences and publish your work in high-impact journals
• Actively contribute to the interdisciplinary research environment of our iFIT Cluster of Excellence and the University of Tuebingen and collaborate with researchers from different scientific fields

Profile

• An excellent Master's degree (or equivalent) in biochemistry, biology, molecular medicine, biotechnology or a related life science discipline
• A strong interest in cancer biology
• Practical laboratory experience in molecular and/or cellular biology
• Communication skills and proficiency in English
• A proactive, independent and team-oriented working style

We are seeking enthusiastic, curious and motivated candidates, who enjoy scientific challenges and collaborative research.

Benefits

We offer an exciting and ambitious PhD project (leading to the degree of Dr. rer. nat.) within the iFIT Cluster of Excellence addressing highly relevant questions in cancer biology with cutting-edge technologies. You will benefit from close supervision and mentoring in a collaborative research environment, many interdisciplinary collaborations with experts of different fields, membership in the iFIT Graduate School with its excellent PhD program and many career development opportunities, as well as participation in international conferences and scientific meetings. Modern Environment

• Innovative university hospital

• State-of-the-art technology

• World-class international research

• Excellent career prospects Career & Development

• Structured onboarding

• In-house academy

• Diverse training opportunities

• Targeted career development Internationality

• Cultural & generational diversity

• Support through language courses

• Integration programmes (nursing) Research

• Cutting-edge research at the highest level

• Support from PhD to professorship Cooperation

• Mission statement, principles of leadership & cooperation

• Employee & management consulting

• Employee representation

• Events, e.g., after-work parties, summer party Mobility & offers

• Good public transport connections

• Parking space sharing & ride-sharing service

• Discounts in the canteen & cafeteria

• Job bike & other corporate benefits

About us

The Faculty of Medicine is one of the four founding faculties of the Eberhard Karls University of Tübingen. With its non-clinical facilities as well as its research and teaching area corresponding to the organisational units of the University Hospital, it is one of the largest medical training and research institutions in Baden-Württemberg.

About the position

Our work combines fundamental cancer research with translational drug development using innovative technologies (e.g. OMICS analyses, organoid models, in vivo cancer models). We investigate how targeting essential cellular processes in cancer cells (such as mitosis, transcription or lipid metabolism) can be exploited to selectively eliminate cancer cells and to overcome therapy resistance. Together with pharmaceutical scientists, we develop highly efficient compounds that target these vulnerabilities. The final goal of our research is to translate our therapeutic concepts into clinical applications. References:

• Rudalska et al. Nat. Cancer 2025, doi: 10.1038/s43018-024-00899-7
• Rudalska et al. Nat. Cancer 2021, doi: 10.1038/s43018-020-00168-3
• Learn more

Contact for questions

Team Recruiting Service

07071 29-80599

Online application to

Dr. Daniel Dauch

Index number: 7735

Including CV and cover letter

Application deadline: 26.08.2026

Apply now

WhatsApp application

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We offer remuneration in accordance with TV-L (collective wage agreement for the Public Service of the German Federal States), severely handicapped persons with equal qualifications are given preferential consideration. Interview expenses are not covered. Please note the applicable vaccination regulations. The employer actively promotes equal opportunities and particularly encourages applications from women.

1 Continued employment will be sought whereever possible.

2 The data provided does not constitute a basis for an employment contract at the University Hospital of Tübingen. It is intended to serve as a rough guide for all interested parties. Remuneration is governed by the applicable collective bargaining agreements in conjunction with the corresponding pay scales. Further information can be found here.

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